Lactobacillus crispatus M247

Lactobacillus crispatus is a bacterial species that is naturally present and found with great frequency in the female urogenital tract, which makes it an ideal candidate for colonizing the vaginal environment.

Among the few L. crispatus strains selected so far, Lactobacillus crispatus M247 is certainly the most studied. All available publications agree on attributing to it a peculiar colonization capacity.

Furthermore, in vitro tests appear to show that Lactobacillus crispatus M247 is insensitive or resistant to high concentrations of metronidazole and boric acid.

Lactobacillus crispatus M247 is capable of:
  • compete with other microorganisms for nutrients and adherence to the vaginal epithelium
  • produce lactic acid and consequently reduce the vaginal pH

These characteristics mean that Lactobacillus crispatus M247 in vitro is associated with an in vitro minimal growth of pathogenic bacteria and fungi, such as Candida, Gardnerella, Chlamydia and Trichomonas.

How it works

Bacterial therapy

The use of bacterial species that are naturally present in the human body as potential protective factors helps to fight the enemies with their own weapons, that is, to fight “bad” bacteria using the power of other “good” bacteria.

This is the idea behind the so-called bacterial therapy.

The prospect is interesting, since it could lead to a reduction in the use of drugs (especially antibiotics) for the treatment of frequent pathologies, and be a potential advantage in combating antibiotic resistance, a very topical problem all over the world.


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